BREEZE-2

Study Design: Multi-centre, wait-list design, randomised controlled trial
Disease Area: Respiratory
Funder: NIHR RfPB
Sponsor: Hull University Teaching Hospitals NHS Trust
Chief Investigator: Dr Ann Hutchinson
Trial registration: ISRCTN13662540

A randomised controlled trial of a complex intervention to manage breathlessness in pulmonary fibrosis (BREEZE-2)

IN SET UP

Summary

Diseases which cause scarring of the lungs called Pulmonary Fibrosis usually affect older adults. They progress over time and make it hard to breathe. Medications can slow disease progress, but do not improve symptoms nor quality of life. Shortness of breath is the most common symptom and the one which has the biggest impact on the lives of those affected. Shortness of breath is also experienced by people with other scarring lung conditions (other fibrotic interstitial lung diseases [ILD]). Breathlessness management training helps people with other lung conditions, but we do not know whether it helps people with lung scarring. It is important that we find out how to help people affected so doctors and policy makers make correct treatment decisions. We will do a research study called a trial to find out if breathlessness management training does help people with pulmonary fibrosis.

What we plan to do

The BREEZE 2 study will see whether breathlessness management techniques can support the breathlessness management at home in people with pulmonary fibrosis.

We aim to recruit 146 eligible adults with pulmonary fibrosis from 15 hospital sites across the UK.

Chief Investigator

Dr Ann Hutchinson Research Fellow - Hull York Medical School, University of Hull

HHTU Study team

Grant Constable - Trial Manager
Bronwen Williams - Operations Manager
Laura Simms - Data Manager

Collaborators

Prof Judith Cohen Director - Hull Health Trials Unit, University of Hull
Helen Roberts Patient and Public Involvement Lead - University of Hull
Prof Miriam Johnson - University of Hull
Dr Flavia Swan - University of Hull
Dr Mark Pearson - University of Hull
Prof Gerry Richardson - University of York
Miss Caroline Wright - Castle Hill Hospital

Email address

breeze2@hyms.ac.uk

Participating Sites and their Project Investigators

  1. University Hospitals Birmingham NHS Foundation Trust - Dr Gareth Walters
  2. Leeds Teaching Hospitals NHS Trust - Dr Alison Boland
  3. NHS Fife - Dr Devesh Dhasmana
  4. North Bristol NHS Trust - Dr Shaney Barratt
  5. Royal Devon University Healthcare NHS Foundation Trust - Dr Michael Gibbons
  6. University Hospitals of Leicester NHS Trust - Dr Rachel Evans
  7. Norfolk and Norwich University Hospitals NHS Foundation Trust - Dr Andrew Wilson
  8. NHS Lothian - Dr Gareth Stewart
  9. The Newcastle Upon Tyne Hospitals NHS Foundation Trust - Dr Anne-Marie Bourke
  10. Northern Health and Social Care Trust - Dr Paul Minnis
  11. Royal Wolverhampton Hospital NHS Trust - Dr Ahmed Fahim
  12. University Hospital Southampton NHS Foundation Trust - Nikki Cullum
  13. James Paget University Hospitals NHS Foundation Trust - Andrei Kisseljov
  14. Manchester University NHS Foundation Trust - Sue Stockdale

Read the Participant Information Sheet here.

Read the Privacy Notice here.

 

Watch this space.